Clinical Trials Information for Patients with Mental Disorders

Do you or someone you know suffer from Mental Disorders?

If so, you may want to learn more about these medical research studies for individuals with Mental Disorders.

Through medical research, physicians are working to find new and more effective treatments that may help those with Mental Disorders.

Our hospital is taking part in such clinical trials aimed at evaluating how people who have symptoms of mental illness respond to new anti-psychotics and study drugs. Some studies of these trials are also happening worldwide. Subjects will be enrolled in the studies only after complying with trial inclusion and exclusion criteria. Detailed trial procedure will be explained to interested candidates, along with their relative or caregiver. Importantly, you can discontinue your participation at any point of time with no questions asked. Trial medications will be available to the subject free of cost for the entire duration of the study and reasonable travel expenses will also be reimbursed. Study patients will be evaluated and looked after carefully throughout the study by a physician.

If you are not suffering from any serious or unstable illness,

If you are not pregnant or lactating or planning to become pregnant,

And if you would like to know more about anything you have just read, please look through the summary of the ongoing trials or contact us to find out more.

I. (A) Six Week Trial Evaluating the Efficacy, Safety and Pharmacokinetics of Flexible Doses of Oral Ziprasidone in Adolescent Subjects with Schizophrenia

Key Inclusion Criteria:

• Primary diagnosis of schizophrenia
• Treated in an inpatient or outpatient setting

Key Exclusion Criteria:

• History of significant cardiovascular disease, cardiac arrhythmias, QT prolongation
• Received an investigational drug within 4 weeks prior to baseline

Gender : Male and Female
Minimum Age : 13 years
Maximum Age : 17 years
Duration of Study : 6 weeks
Commitments : Participants to come for 6 scheduled visits and spend approximately half a day for certain visits.

I. (B) 26-Week Open-Label Extension Study Evaluating the Safety and Tolerability of Flexible Doses of Oral Ziprasidone in Adolescent Subjects with Schizophrenia

Key Inclusion Criteria :

• Must have received study medication in the previous study (A)

Key Exclusion Criteria :

• Experienced cardiac arrhythmias or QTc prolongation during the preceding study

Gender : Male and Female
Duration of Study : 26 weeks
Commitments : Participants to come for 8 scheduled visits and spend approximately 2 hours for certain visits

For more information, please contact: Ms Yeo Sook Kwan (6389 2960)

II. Epidemiological Study in Asian Patients with Acute Major Depressive Disorder

Key Inclusion Criteria :

•  New or first onset of acute major depressive disorder.
•  Agreeable to be treated with an antidepressant medication.
•  Free from acute symptoms of depression for at least two months prior to the onset of the present symptom.

Key Exclusion Criteria :

•  Previous diagnosis of schizophrenia, schizophreniform disorder, schizoaffective disorder, bipolar disorder or dementia.
•  Experiencing chronic pain.
•  Current symptoms of depression have been persistent for more than 6 months.

Gender: Male and female
Minimum age: 18 years
Maximum age: 70 years
Duration of study: 3 months

Please note that more specific inclusion/exclusion criteria must be met prior to entering the trial.

If you or someone you know who is interested in participating in this clinical trial, please do not hesitate to contact us at :

Clinical Trial Unit
Research Department
Institute of Mental Health & Woodbridge Hospital
Buangkok Green Medical Park
10 Buangkok View,
Singapore 539747

Tel (O) : (65) 63892962
Fax : (65) 63150548

Contact Details:

Ms Elaine Pek
Assistant Manager
Email: elaine_pek@imh.com.sg
Tel: 6389 2961

Ms Jaclyn Ong
Clinical Research Coordinator
Email: jaclyn_yy_ong@imh.com.sg
Tel: 6389 2959

Ms Grace Chen
Study Coordinator
Email: grace_suhua_chen@imh.com.sg
Tel: 6389 2960

Ms Jenny Tay
Study Coordinator
Email: jenny_am_tay@imh.com.sg
Tel: 6389 2789